Powder Scientist
About our client
To strengthen our materials Science team, based in the Pharma Sciences Department in Braine, Belgium, our client is looking to fill the position of: Powder Scientist.
About your role
Would you say your scientific approach is passionate above all? As a Powder Scientist you like to work in an environment where you can:
· Participate to the development of new products and processes
· Give directions from early development up to lifecycle management, from particle design up to final product
· Work autonomous, well-organized and use your pro-active thinking skills
· Be self-reflective on the gathered data
· Use your creativity to develop new analytical methods or even develop new technology
· Drive team spirit and encourage collaboration
Your responsibilities:
· Being a leader in powder characterization by leveraging Materials Science to drive overall Product Development in order to obtain the right drug for every patient
· Guide the Product Development by connecting powder /particle insights with manufacturing technologies and overall product performance
· Combine particle knowledge with crystallization science to optimize expected powder properties
· Developing method and performing analyses on active ingredient, drug product and excipients in the field of powder characterization
· Independently planning, conducting and interpreting experiments to determine the bulk powder and particle properties of raw materials, intermediates and final dosage forms, by mastering a number of characterization tools: laser diffraction (wet and dry method) and microscopy (optical and SEM) for particle size and shape measurements; gas pycnometry and fine solid displacement methods for true and envelope density determinations; physisorption for surface area quantification and porosimetry; powder rheometry to assess powder flow stability and strain-rate dependency; shear cell testing to measure powder flow functions and wall friction with application to hopper design; surface energy and wettability analyses via contact angle measurements (sessile drop, Washburn and Wilhelmy plate methods), standardized and customized methods to evaluate bulk/tapped density, powder compressibility, permeability, mechanical strengths of tablets and/or agglomerates, electrostatic charging, segregation, sticking and caking propensity; dynamic vapor sorption to assess powder hygroscopicity; differential scanning calorimetry (DSC) and thermogravimetric analysis (TGA) to understand the powder thermal behaviour.
· Performing chemical imaging on drug product or intermediates
· Being the reference person in powder characterization and training colleagues
· Applying QbD principles, multivariate analyses, and being in support of PAT development
· Keeping track of literature and state of the art scientific practices, and implementing innovative solutions
· Communicating with stakeholders and external partners (universities, centres of expertise…)
· Writing reports and give internal and external presentations
Education, experience, and skills required:
· Master / PhD in chemistry, pharmaceutics, physics or engineering or equivalent experience, on powder characterization
· Fluent in English
· Ability to work at the interface
· Able to combine multiple tasks and work simultaneously on different projects
· Soft skills: entrepreneurship, motivated, enthusiastic, reliable, team player, good communication
Our offer
Jefferson Wells offers you a permanent contract as a consultant with an attractive salary package and access to training in both technical and non-technical skills. We'll be your career partner every step of the way.
Are you interested in this position? We invite you to apply. Do you have any questions? Please contact Aylin Ugurlu at [email protected]
