Non-Clinical formulation Scientist
Contracting – Braine l’Alleud
The Responsibilities
- Manages Non-clinical formulation activities related to the screening and CMC development of small molecule, peptide or other synthetic drug products (from discovery and preclinical stages to clinical formulation orientation work for First-In-Human). Typical formulations are microsuspensions, amorphous solid dispersions, and nanosuspensions.
- Liaises with Non-Clinical formulation Leads to assure consistency between the development and the production of NCL formulation, and the project needs.
- Manages protocols of development or production and participate to the planning of activities.
- Participates to the development, characterization, and production of non-clinical formulations.
- Performs the physico-chemical characterization and stability studies of new molecules (NCEs) on batches before the GLP batch. Typical characterization techniques are liquid chromatography (UPLC), thermal analysis (DSC, TGA), laser diffraction granulometry, optical and electron microscopy. Develops if needed new methods.
- Analyses results with readiness to criticize and ensures the consistency of these results with earlier data if relevant.
- Documents and verifies in an appropriate manner the whole of the performed activities (e.g. Electronical Lab Notebook)
- Consolidates the results and write adequate reports.
- Contributes to the writing of technical documents like SOPs, user guides, guidances, etc.
- Participates to the advancement of the department’s Science & Technology and Innovation projects The scientist needs to be autonomous and think pro-actively, in collaboration with the Non-Clinical formulation lead. The need to already have an experience in formulation with a preference for Non-Clinical formulation development, with knowledge in the related analytical support. He needs to be flexible, well-organized, curious and have good communication and coaching skills. He needs to be able to combine multiple tasks and must adapt to priority changes.
Skills and Knowledge Requirements
- Master/PhD: pharmaceutical sciences, formulation, analytical chemistry or equivalent
- Min years’ experience required: 2-3 years in formulation domain, preferentially in non-clinical formulation field.
- Key technical backgrounds: non-clinical formulation preparation, small molecule chromatography (HPLC/UHPLC)
- Mandatory skills: team player, communicative, experience in a similar position/environment, compliant/rigorous, flexible, curious
Our Offer
Jefferson Wells offers you a permanent contract as consultant with an attractive salary package and will give you access to trainings in technical matters and soft skills. We will be your career partner for each step along the way.
